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And maintaining even that requires ongoing vigilance.300 minutes per week of physical activity, constant dietary monitoring, unwavering motivation

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N Engl J Med 2016;375:18341844 [DOI] [PubMed] [Google Scholar] 5

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Researchers spent years assuming any compound that touched the glucagon receptor would undermine the glucose control that made GLP-1 drugs useful in the first place

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This does not mean every patient has the same outcome, but it does mean patients should not stop medication abruptly without discussing nutrition, activity, dose strategy, hunger return, and follow-up with a physician

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