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Udayakumar et al
After significant weight loss, many people are no longer trying to become smaller
Dose escalationthough sometimes necessaryis less reliable than medication switching for breaking true tolerance
A 10% weight loss can result in a more than 20% improvement in OSA severity
The excess returns to the vial
Mounjaro and Zepbound use tirzepatide , which targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
