glp 1 drugs vs metformin Synergistic effects of with liraglutide against endothelial dysfunction through GLP-1 receptor and PKA signalling pathway Current Insights, Advantages and Challenges
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Smits MM, van Raalte DH, Tonneijck L, Muskiet MH, Kramer MH, Cahen DL
GLP-1 receptor activation chiefly enhances systemic insulin sensitivity and decreases liver lipid accumulation through indirect mechanisms
At the tissue level, GLP-1 agonists diminish ectopic fat accumulation in the liver and muscle, enhancing insulin sensitivity
