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GGA is normally asymptomatic but can present with pruritus

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Fat sources include olive oil, avocado, fatty fish, fatty meats, nuts, seeds, MCT oil (typically used as a supplement), butter, lard, or egg yolks, while carbohydrate sources include mainly vegetables and nuts [42]

The framework below maps common preclinical aims to the more appropriate reference compound

It is unclear whether the itching side effect is obeticholic acid-specific or associated with bile acid metabolism in general

The randomization list was generated using validated software, which involved a pseudorandom number generator, and was stratified according to the presence or absence of T2D