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In a crossover trial evaluating semaglutide versus placebo as an add-on to automated insulin delivery therapy in adults with type 1 diabetes, the use of semaglutide was associated with an increased percentage of time spent within the target glucose range, along with reduced insulin requirements.

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Notably, their work contributed to the development of GLP-1 drugs, which have revolutionized treatment for type 2 diabetes and obesity
A study in Nature found a specific genetic variant that may boost the effectiveness of GLP-1 weight-loss drugs like semaglutide and tirzepatide.

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