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Today, more people than ever before are facing the challenges of obesity, diabetes, and arthritisoften all at the same time

The rapid bi-weekly dose escalation protocol may have contributed to higher GI event rates

Wegovy typically requires gradual dose adjustment and is part of a comprehensive weight management programme

In today's article (part 1), Ill talk through how these medications work

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A GLP-1 agonist reduced conditioned place preference for food rewards as well as motivated behavior for sucrose in a progressive ratio operant-conditioning paradigm in rodents via two key nodes of the reward system: the VTA and NAc (Dickson et al., 2012)