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The Medicines and Healthcare products Regulatory Agency (MHRA) has warned healthcare professionals to be aware of the potential risk of pulmonary aspiration in patients using glucagon-like peptide-1 (GLP-1) or dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (GLP-1 RAs), who undergo surgery or procedures with general anaesthesia or deep sedation

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Semaglutide is not a short-term fixmost patients benefit from ongoing treatment to maintain weight loss and metabolic improvements

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Weight loss on compounded semaglutide typically becomes noticeable within 4-12 weeks, though individual timelines vary based on dose, metabolism, and genetic factors