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In 2025, the Endocrine Society reported signals from preclinical and early clinical research suggesting that GLP-1 receptor agonists may reduce nicotine- and alcohol-seeking behavior and the risk of relapse

Furthermore, in periodontal disease, liraglutide was also found to downregulate M1-associated surface markers and cytokines, such as CD11c (Itgax), thereby reducing the proportion of M1 macrophages in gingival tissues and alleviating alveolar bone loss

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Draznin B, Aroda VR, Bakris G et al (2022) 9