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[16] In some cases, switching to an alternative agent with different pharmacokinetic properties or discontinuing therapy may be necessary if symptoms significantly impair quality of life or pose health risks

In fact, these drugs are approved for use alongside a comprehensive diet and exercise regimen

Additionally, GLP-1 has been shown to enhance the proliferation and differentiation of endothelial progenitor cells through upregulation of VEGF, potentially promoting angiogenesis that could contribute to retinal complications [101,102]

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If found to be efficacious, safe, and have a long-term impact, Akkermansia supplementation has massive potential to open new doors for lifestyle disease interventions