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In addition to glycemic and weight loss efficacy, for patients with obesity with or without diabetes, benefits are seen in heart failure with preserved ejection fraction (HFpEF) with semaglutide [8,9,10] and tirzepatide [11]

Male mice underwent 60- minute habituation in the test arena before first receiving tirzepatide treatment and then 30 minutes later an alcohol injection

By combining ideas from endocrinology and scientific research, we can tell a full story

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So even outside controlled trials, both medicines produce substantial weight loss

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