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Area postrema mediation of physiological and behavioral effects of lithium chloride in the rat

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Confirmatory secondary endpoints are change from baseline in AD Cooperative Study Activities of Daily Living MCI (ADCS-ADL-MCI) score and time to progression to a CDR global score of 1.0 among participants with a CDR global score of 0.5 at baseline, both assessed at week 104 (see discussion and Table 2)

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Injection Site Selection and Rotation Protocols All Phase 2 retatrutide dosage cohorts used subcutaneous injection as the delivery route
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