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Patients who combine medication with a reduced-calorie diet and regular exercise typically see faster, more substantial results than those relying on medication alone

If appetite rebounds significantly at any step, pause the taper for an additional four weeks before continuing

Cue reactivity (CIRO model): Cues show up like seeing a snack or smelling popcorn

[141] [142] [143] As of 2024 [144] federal Medicare Part D does not cover weight-loss drugs, and only a few federally-funded, state-administered Medicaid plans cover drugs for obesity

16 Cardiovascular outcomes The cardiovascular outcomes trial for tirzepatide, SURPASS-CVOT, is an active-comparator study versus dulaglutide 1.5 mg weekly and is ongoing

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