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Description
The recent data provide evidence that GLP-1R activation affects the mechanisms of signal transduction associated with insulin resistance, energy homeostasis of the brain, neurogenesis, synaptic functioning, neuroinflammation and other cell responses to stress, pathological protein aggregates, proteostasis, the cerebrovascular system, and the BBB [42]
Our data provide a rational template to facilitate the design of better GLP-2 analogues for therapeutic use and expand our knowledge on the biology of this receptor family

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Baseline weight and BMI will be recorded
