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One in eight Americans now use GLP-1 weight loss drugs like Ozempic and Wegovy

Ozempic is also approved to reduce the risk of heart attack, stroke, or death in adults with T2DM and known heart disease

The 2.4 mg weekly maintenance dose is where the phase 3 monotherapy trials showed the strongest results, with an average body weight reduction of 11.8% over 68 weeks

Where These Medicines May Fit in Future Care The future role of these agents depends on evidence, approval decisions, safety data, and real-world use

A small but significant percentage of users, estimated at less than 2% in clinical trials but potentially higher in real-world use, develop gastroparesis symptoms that persist even after stopping the medication