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DOI: 10.1056/NEJMoa2307563
The phase 2 semaglutide NASH trial (published in NEJM, 2021) demonstrated NASH resolution in a significant proportion of patients, though fibrosis improvement was modest

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P =0.02), such that changes in waist circumference were estimated to account for 33% of the effect of semaglutide on MACE risk reduction

coli , though, is not edible, as it is laden with endotoxins that can trigger a septic shock