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GLP-1, a 30-amino acid peptide, is produced from the pre-proglucagon within enteroendocrine L-cells located in the GI tract [41]
By neutralizing oxidative stress, glutathione can minimize the appearance of fine lines and wrinkles, giving the skin a smoother, more youthful appearance
PKF275-055, an analogue of vildagliptin and a DPP-4 inhibitor, counteracted changes in Na/K-ATPase activity, nerve conduction velocity, and nociceptive thresholds in diabetic rats [50]

Berberine Action: Improves insulin sensitivity, regulates blood sugar, supports gut microbiota indirectly stimulates GLP-1 Dosage: 500 mg 2-3 times a day (before meals) Efficacy: Equivalent to metformin (a diabetes medication) in some studies 2
