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However, when food remains in your stomach longer, acid exposure to the esophagus can increase, potentially triggering heartburn or acid reflux in people with pre-existing GERD
On the standard 4-week titration protocol, reaching the 12mg maintenance dose takes approximately 12 weeks
doi:10.1016/j.ajo.2025.12.015 32.Shor R, Mihalache A, Noori A, et al
Diz-Chaves Y, Maastor Z, Spuch C, Lamas JA, Gonzlez-Matas LC, Mallo F
Hiccups are not listed as a primary side effect in major semaglutide clinical trials, meaning they occur rarely and unpredictably
However, you should only consider it under medical supervision
