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This gap signals need to investigate potential barriers like inconsistent dosing, inadequate caloric deficit, medication interactions, or metabolic factors limiting response

Liz Brody is an award-winning journalist and the former health and news director of O, the Oprah Magazine and Glamour.

This is a potent prescription medication that changes how your body manages appetite, insulin, and fat storage

This is the best-case scenario and happens for roughly 60% to 70% of nighttime injectors
Having these criteria defined before starting treatment removes the pressure of making judgment calls in the moment

But heres whats encouraging: even the 18% of participants who hadnt hit that 5% mark by week 12 (so-called late responders) went on to achieve clinically meaningful weight loss by week 72 in 90% of cases
