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Similarly, patients with a pronounced metabolic phenotype, characterized by high baseline triglycerides, elevated apolipoprotein B, and poor glycemic control, might be ideal candidates, as these are parameters directly and favourably modulated by these agents [36]

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In severe cases, the tissue may need months to fully normalize

S., Catarig, A

I worked with a practitioner: We optimized my hormones with bioidentical HRT (alongside all of the foundational food & lifestyle things I had already integrated CANT skip this part folks!) AND I decided to try a very low dose of semaglutide (a GLP-1 agonist) When I say low dose, I mean low : I started at 50 mcg I am now at 100 mcg For context: pharmaceutical semaglutide (like Ozempic/Wegovy) typically starts around 0.25 mg0.5 mg (250-500 mcg) and goes up to 2.4 mg