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Psychiatric side effects, though rare with GLP-1 agonists, warrant prompt attention

Overall prescribing trends The study found that 1,162,662 patients were prescribed a GLP-1 RA between January 2018 and June 2024, with 4,815,135 total prescriptions during this period

16 Matthias Tschp and his team discovered that dual agonists targeting both GLP-1 and GIP receptors (GIPR) are more effective in treating diabetes than those targeting only GLP-1R

While it has been shown that moderate exercise can lead to healthier weight loss with GLP1-RAs 37,38 , it is difficult to get patients to adhere to such regimens outside of controlled trials

Before we dig into the data, lets look at the biological plausibility here

New research unveiled at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM25) in Barcelona has highlighted the complexity that these drugs introduce into metabolic imaging, signaling a need for revised evaluation protocols to avoid diagnostic pitfalls