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it contributes to the development of PCOS and worsens [161] its clinical features, primarily due to hyperinsulinemia resulting from insulin resistance, which increases ovarian androgen production [162, 163]

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54 Early observational studies raised concerns regarding a potential association between GLP-1 RA therapy and pancreatitis

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doi:10.1016/S2213-8587(17)30085-2 Marso SP, Bain SC, Consoli A, et al