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However, unlike GLP-1R agonists, DPP-4 inhibitors do not cause significant reductions in body weight (Meneghini et al., 2011

Salcedo, I., et al

Third, many compounded GLP-1 drugs are being sold illegally online, with some falsely labeled for research use only. The FDA is also monitoring illegal marketing and inconsistent manufacturing practices

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Semaglutide (Wegovy pill), a once-daily tablet that must be taken with a small amount of water first thing in the morning, a half hour before any food and semaglutide (Wegovy injection), or a weekly injection through a pen that must be kept refrigerated

Additionally, 36.8 percent of patients treated with Wegovy experienced improvement in fibrosis with no worsening of steatohepatitis, versus 22.4 percent in the placebo group