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Independently of these peripheral actions, GLP-1RAs show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, bloodbrain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion

Chelsea Handler shared that her doctor handed her Ozempic in case she ever "wanted to lose five pounds." Scroll down to hear the comedian's experience with the type 2 diabetes drug.