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Comparison of the effects of twice-daily exenatide and insulin on carotid intima-media thickness in type 2 diabetes mellitus patients: a 52-week randomized, open-label, controlled trial
Early-stage studies revealed an initial increase in 24 h ambulatory SBP, which subsided over time, leading to a net reduction in SBP
A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release
Raz I, Wilson PW, Strojek K, et al
Int J Clin Pract Suppl 2010
So, while GLP-1s might be helpful, the risk-benefit trade off for these groups might not be worth it
