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Tirzepatide, the first approved dual GIP/GLP-1 receptor agonist, is a 39-amino acid peptide with an approximately 120-hour half-life supporting once-weekly dosing

"Lilly's tirzepatide successful in phase 3 study showing benefit in adults with heart failure with preserved ejection fraction and obesity" (Press release)

doi: 10.2337/db10-0128

The study is conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Ethics Committee of the Medical University of Bialystok (Project identification code: R-I-002/546/2015)

Stopping these drugs without a clear reason may work against those benefits

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