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GLP-1 Receptor Agonists and Atherosclerosis Protection: The Vascular Endothelium Takes Center Stage

An observational microbiome study by Yassour et al., 2018 shows moderate risk of bias, primarily related to variability in sequencing depth and analytical pipelines
Finally, the familywise error rate (FWE) threshold to correct for multiple comparisons was calculated through iterations using a Monte Carlo permutation procedure

Patil SP, Ayappa IA, Caples SM, Kimoff RJ, Patel SR, Harrod CG
The surprising thing is that it took the market a really long time to realize the GLP-1 threat
In addition to their effects on - and -cells, GLP-1 analogs reduce hepatic glucose production, appetite, and gastric motility, which are responsible for weight loss
