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[11] A systematic review and meta-analysis found that, using randomized controlled trials, that semaglutide is efficacious for sustained weight loss in patients with overweight/obesity and without diabetes

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Liraglutide mimics a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate the release of insulin when you eat

Documented Outcomes Prescription semaglutide and tirzepatide have undergone Phase 3 randomized controlled trials demonstrating average weight loss of 10-22 percent over 68 weeks

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