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Description
Incretin-Based Therapy and Type 2 Diabetes
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An interesting cross-talk between the glucagon-like peptide-1 receptor axis and angiotensin receptor pathway for modulation of renal sodium handling in obesity

Cheung says

Whether you are currently using semaglutide, considering starting it, or simply trying to separate fact from fear, the evidence may surprise you
Semaglutide medications work by activating the GLP-1 receptor alone, while tirzepatide medications activate both the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor, creating what is commonly described as a dual incretin mechanism
