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Liraglutide (Saxenda) NICE Technology Appraisal TA664 recommends liraglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, within a specialist weight management service

However, in practice this never happens

Additionally, people who have taken appetite suppressants in the past or those with certain genetic variations in GLP-1 receptor pathways may experience a reduced response to standard dosing

GLP1s may offer midlife women other benefits besides weight loss

Death During Surgery Though extremely rare, people have died during surgical procedures meant to resolve the adverse side effects of Ozempic and Wegovy