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Overall, indirect comparisons suggest that SGLT2 inhibitors may offer greater preservation of eGFR than GLP-1 receptor agonists in a broader population of people with type 2 diabetes mellitus and CKD

A Phase 3 trial is expected to be completed later this year

Effects of high-protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial

Then came Tirzepatide (Mounjaro/Zepbound) , a dual-hormone agonist pushing results closer to 21%

How The Study Was Built The investigators used the TriNetX US Collaborative Network and identified 841,831 eligible adult women with breast cancer across 68 healthcare organizations

Now, new research suggests there may be another benefit: The combination of a GLP-1 drug with menopausal hormone treatment (MHT) may aid in weight loss more than a GLP-1 taken alone, and it may provide some cardiovascular benefits, too