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We will continue to scrutinise the data to see whether abnormal blood test results such as having pre-diabetes might predict a better response to exenatide, and whether there were more of these people in the earlier, smaller trials in which we found positive overall effects. The trial was supported by the UCL Comprehensive Clinical Trials Unit (UCL CCTU), the National Institute for Health and Care Research (NIHR), UCLH Biomedical Research Centre and the NIHR UCLH Clinical Research Facility

Cell Metab (2018) 27:74056

About 9-10% of participants stopped treatment because of side-effects mainly gastrointestinal issues compared with 4-5% in the semaglutide groups

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When rapid weight loss is medically necessary : Before bariatric surgery, for joint replacement candidacy, or when weight directly threatens cardiovascular health

Gastric control of food intake