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Another study in the American Journal of Respiratory and Critical Care Medicine documented that GLP-1 users with baseline sleep apnea showed apnea-hypopnea index (AHI) improvements averaging 48% at 12 months

It is not labeled for human or veterinary use

But the meal-stimulated response is blunted: up to 25% lower in prediabetes, and significantly reduced in lean women with PCOS

Phase 2 trial (NEJM 2023) randomized 338 adults with obesity to retatrutide doses from 1 mg to 12 mg/week

The safety profile for semaglutide recommends that anyone with a personal or family history of some thyroid cancers shouldnt use semaglutide
