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This is an experimental technique that can further characterize C10 membrane perturbation by computing the insertion fraction of C10 into the membrane on the micro-second level [72] and predicting the behavior after membrane insertion, i.e., flip-flop or migration from the membrane to the aqueous phase [75]

Laboratory evaluation may include complete blood count, iron studies (ferritin, iron, TIBC), comprehensive metabolic panel, thyroid function tests, and vitamin B12 and vitamin D levels

Patients treated with WEGOVY injection (mean baseline body weight 95.4 kg) achieved an average of 10.5% weight loss from baseline at Week 72, and patients treated with placebo (mean baseline weight 97.6 kg) achieved an average of 2% weight loss from baseline at Week 72

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