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Moreover, while GLP-1RAs show efficacy across multiple addictive substances, the magnitude and nature of these effects likely depend on the neurocircuitry engaged by each drug class

Naltrexone (Revia) is an opioid receptor antagonist that competitively binds to opioid receptors

Wegovy is self-injected once a week at any time of day in the stomach, thigh, or upper arm

Synthesizing it correctly requires sophisticated equipment and quality control

In contrast, phentermine is approved to manage weight in adults and children ages 17 and older with obesity or who are overweight with weight-related conditions

Weight loss was not only compared with a placebo group, but also to another substance in the GLP-1 receptor agonist class called Liraglutide