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While it helps to leverage existing real-world data for cost-effective and time-efficient insights, this method can be challenged by potential biases, missing data, and lack of control over variables or study design

The increased availability of NO is essential, as it counteracts oxidative stress and inflammation, which are significant factors contributing to cardiovascular disease (Saijonmaa et al., 1997

Optimal Candidates Patients with BMI 30 or higher without contraindications represent the core target population

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Off-label use can lead to dosing errors and reduced efficacy

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