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Of these, three RCTs were included, comprising 640 patients [5,9,13]

A phase 2 trial published in the New England Journal of Medicine reported substantial average weight reduction in adults with obesity or overweight

Participants received the maximum tolerated dose of either Zepbound (10 mg or 15 mg) or Wegovy (1.7 mg or 2.4 mg), alongside diet and exercise counselling

In an interview at the HLTH conference in October 2024, Noorian told Endpoints that Empowers revenue historically grew at a rate of about 40% a year, but thanks to GLP-1s, revenue growth had doubled in the past year

This often leads to fast regain
