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Description
Lixisenatide is a daily GLP-1RA developed by Zealand Pharma, which prolongs its half-life through structure-inducing probe technology based on exendin-4/exenatide
While tirzepatide and weight loss generally improve blood pressure over time, the early weeks of combination therapy can involve unpredictable blood pressure fluctuations
Diabetes 61 (5), 12501262 (2012)
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The promise of GLP-1s to address these concerns is understandably appealing, but we lack adequate research to guide evidence-based prescribing and patient decisionmaking for this population
Catalano PM, Shankar K
