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Acknowledgments We thank the study participants, and the investigators and study site staff who conducted the study

Regular Diabetes Reviews Ensure you attend scheduled diabetes reviews where your healthcare team can assess both the efficacy of Ozempic for glycaemic control and the tolerability of treatment

A 2025 study published in the New England Journal of Medicine followed people who took 25 mg of oral semaglutide daily and found that they lost 13.6 percent of their body weight after 64 weeksvery similar results to other studies looking at weight loss on the highest dose (2.4 mg) of the weekly injectable version

Smith MH

For weight loss injections, this could mean using a drug approved for diabetes for weight management purposes, or using a drug at a dosage not specifically listed for weight loss

Liraglutide treatment results in the increased phosphorylation of AMP-activated protein kinase (AMPK) and the reduced phosphorylation of mammalian target of rapamycin (mTOR)