glp 1 agonists contraindications Incretins: How we got here, where we're at and what is coming next GI Adverse Effects of Glucagon-Like
Description
SGLT-2 Inhibitors: The Gap Seems to Be Leveling Off

Pasqualotto et al
Flannery PJ, Trushina E

391 GLP-1 and GLP-1 analogs exert their effects on food intake and body weight through a myriad of neural substrates, encompassing several hypothalamic nuclei (including the arcuate nucleus of the hypothalamus, periventricular hypothalamus, and lateral hypothalamic area), hindbrain nuclei (such as the parabrachial nucleus and medial nucleus tractus solitarius), the ventral subregion of the hippocampus (vHP), and nuclei embedded within the mesolimbic reward circuitry (including the ventral tegmental area, VTA, and nucleus accumbens, NAc)
Their tendency to cause weight loss is thrusting them into a significant role in the management of obesity

Interleukin-1 (IL-1) receptor antagonist gene polymorphism in normal weight obese syndrome: relationship to body composition and IL-1 alpha and beta plasma levels
