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If successful, it would offer GLP-1 activation without peptide stability concerns, cold chain requirements, or injection needles

The paper closed with a careful prediction: there likely existed an endogenous mammalian analog to the exendin peptides. He was describing GLP-1 without knowing it had already been found

Putur is not ready to give that up

You need a concentration that works at both your starting dose and your eventual maintenance dose

Furthermore, the ability of GLP-1R agonists to ameliorate neuropathy-related complications, such as cognitive deficits, underscores their broader neuroprotective benefits [43, 44]

In short, both are effective, but theyre not identical in how they work