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This dual action sets it apart from older diabetes medications that focus on one pathway

Inhibition of DPP-IV has been associated with immunomodulatory effects, resulting in enhanced T-cell function and immune responses

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In a 12-week RCT (n=101), the same oral medication plus structured behavioral support led to: Greater weight loss (4.2% vs 2.7%) More clinical responders (60% vs 37%) Better habit and psychological outcomes No safety trade-offs Medication alone optimal outcomes

Side Effects of Tirzepatide (Mounjaro) You Should Expect The most common tirzepatide side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain, affecting up to 2530% of users in clinical trials

Hormonal Changes Hormonal fluctuations, particularly during pregnancy, menstruation, or menopause, can cause heart palpitations