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Their neglect has often resulted from early adverse events attributable to poor pharmacokinetic design, incomplete receptor mapping, or the absence of enabling technologies now considered routine, such as long-acting peptide conjugation, tissue-selective targeting, and signal-bias optimization

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Blood (25 L) was collected from the saphenous vein using minicaps Na-hep Micro Capillary Pipettes (Hirschmann Laborgerte) for up to 12 days