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Butyrate possesses unique cell-signalling properties which have shown effects of decreasing insulin resistance in humans, increasing GLP1 production by intestinal cells & the liver, while also sensitizing our body to the effects of GLP-1 [3]

Scientific Formulation, Synergistic Action

By inhibiting DPP-4, these agents extend the life of the bodys own GLP-1, allowing it to remain active longer and sustain its natural effects on glucose regulation

However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period

Therefore, the obesity control guidelines strongly recommend lifestyle interventions along with medical treatment for patients who are overweight