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Michael Snyder, MD, Medical Director of the Bariatric Surgery Center at Rose Medical Center, says rapid weight loss can change posture and muscle support, leading to back pain
Instead of just suppressing appetite, it goes into the body and flips the switches for energy production and fat burning back to the "ON" position

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
Patients currently on semaglutide who have hit a weight loss plateau often see renewed progress when transitioning to tirzepatide, likely due to the additional GIP receptor activation
[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Chen Y., Ren R., Yan L., Zhou Y., Sun R., Song H., Yan H., Li Y
