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In fact, GLP-1 RAs are able to delay gastric emptying and to slow intestinal motility in the gastro-intestinal tract, which enhances the feeling of early satiety at a central level [45]

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N Engl J Med (2015) 373(1):1122

In general, this is a safe and accepted practice when a doctor is the one prescribing or recommending off-label usage

The British Menopause Society advises considering transdermal options, like patches or gels, which bypass the digestive system and maintain more stable hormone levels

While relatively few studies ask about sex differences, those that do often find that the physiology and pathophysiology of feeding behavior exhibit sex-specific differences in both animals and humans