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Any meaningful comparison between semaglutide and tirzepatide requires both to be at steady state

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Multivariate analysis of fasting glucose showed that fasting glucose was lower in the placebo arm at 12 months (2.2 mmol/L 95%CI: 0.4, 4.1, p = 0.027) but not at 6 months (1.4 mmol/L, 95%CI 1.1, 3.9, p = 0.24) (Supplementary Tables 10.1 and 10.2)

If youre prescribed a GLP-1 medication, storing it properly is just as important as taking it consistently

2025 GLP-1 research shows that GLP-1 agonists like semaglutide and tirzepatide not only help reduce weight but may also play an indirect role in improving cardiometabolic outcomes, such as blood pressure and lipid profiles

Both drug labels now include ileus, a condition where normal intestinal muscle contractions stop entirely, as a potential adverse event