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Recent evidence showed that Tirzepatide (TZP), a new drug including both Glucagon Like Peptide 1 (GLP-1) and Glucose-dependent Insulinotropic Polypeptide (GIP) receptor agonism, is effective in subjects with type 2 diabetes (T2D), lowering body weight, fat mass and glycated hemoglobin (HbA 1c ) also in obese or overweight adults without T2D

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Repeated episodes of myocardial stunning or chronic low myocardial blood flow can lead to cellular changes such as resorption of the contractile apparatus in order to decrease oxygen demand and allow the myocardial cells to survive

Beyond total calorie intake, nutritional quality is paramount for individuals on GLP-1 therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 202.Bloomer R., et al
