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GLP-1based therapy is also mentioned in the 2026 ADA Standards of Care as part of risk-based treatment options for many adults with type 2 diabetes

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Initial efforts to reduce -cell mass via partial pancreatectomy resulted in PBH recurrence in a substantial fraction of patients 135 , suggesting that islet function rather than mass drives surgery-induced insulin secretion 136

Retrieved from Bezin, J., Gouverneur, A., Pnichon, M., et al

Studies show that semaglutide can lead to significant weight loss, particularly in individuals with obesity (BMI 30) or overweight individuals (BMI 27) with weight-related health problems