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Zepbound is not covered for obesity under Medicare Part D as of 2026

However, a 2025 study in the Journal of the Endocrine Society found no confirmed association between tirzepatide and medullary thyroid cancer in humans

See the CMS-0057-F prior authorization final rule for how the January 1, 2026 regulation affects UHCs mandate

Nevertheless, its translation into clinical practice remains uncertain and further human studies are needed to confirm its therapeutic potential[91,92]

This gives a clinician your medical history, current medications, and treatment goals

Certain surgical procedures call for pausing GLP-1 medications beforehand due to concerns about aspiration risk under anesthesia from slowed gastric emptying