tirzepatide vomiting Dosing Tirzepatide vs. Gastroparesis Side Effects:

Fewer GI issues during training GI distress is the most common reason athletes discontinue GLP-1 medications

Injections are given subcutaneously abdomen, thigh, or upper arm are best

Semaglutide has a more favorable safety profile with primarily gastrointestinal side effects that typically resolve over time

Current pregnancy, breastfeeding, and active conception planning are screened directly because this class of therapy is not appropriate during those windows

However, it has since been removed

doi: 10.3389/fendo.2025.1683419 Received 12 August 2025 Revised 04 December 2025 Accepted 30 December 2025 Published 23 January 2026 Volume 16 - 2025 Edited by Claudia Lagranha, Federal University of Pernambuco, Brazil Reviewed by Lei Zhao, China Medical University, China Michihiro Takahashi, Takahashi Psychiatric Clinic, Japan Sundararajan Mahalingam, University of Nebraska Omaha, United States Rodolfo Nunes, Federal University of Ceara, Brazil Updates Copyright 2026 Doval-Caballero, Ferreira-Hermosillo, Eugenio-Ponce, Garca-Senz, Ibarra-Salce, Tenorio-Rojo, Luna-Avila, Gete-Palacios, Prez-Hernndez, Rojas-Miln, Lpez-Cruz and Mndez-Hernndez